The endometrium is too thin to be pregnant? This new technology will help you solve it!
Ms. Liao, 34, has been too thin for many years to successfully conceive her pregnancy. After the intrauterine injection of autologousbone marrow stem cells, her intima thickness increased by 1-2 mm. After transplanting two blastocysts, she successfully graduated and has now delivered successfully. On the 26th, the reporter learned from the Reproductive Medicine Center of the Sixth Affiliated Hospital of Sun Yat-sen University that there have been many cases of uterine endometrial patients who have undergone intrauterine transplantation of autologous stem cells for successful pregnancy and delivery. This means that women with factors that are thin and unable to conceive the endometriumhave found a new solution.
There are about 10 million abortions every year. Experts caution that abortion should be cautious.
Abortion has become a high-frequency word for the development of gender relations. The data show that in the past 10 years, the average annual number of abortions in China is about 8 million to 10 million, which is much higher than that of developed countries, and it is characterized by normalization, rejuvenation and high repetition rate.The high rate of abortion leads to complications such as pelvic inflammation, intrauterine adhesions, endometriosis, and secondary infertility.In order to treat complications, women need to perform repeated uterine operations, which leads to thinning of the endometrium. Some patients with intrauterine adhesions have severe symptoms such as severe destruction of the lining of the endometrium. The low regenerative capacity of the endometrium and glands also leads to aplastic failure of the intima.Liang Xiaoyan, director of the Reproductive Center, said: "90% of intrauterine adhesions are related to abortion." She cautioned that treatment of abortion must be cautious, which means that women will bear intrauterine adhesions, thinning of the uterus, and fertility difficulties in the future. risks of.
Stem cell transplantation helps successful pregnancy in patients with thin endometrium
For a successful pregnancy, quality embryos and good endometrium are indispensable. The ideal endometrial thickness is the key to ensuring successful embryo implantation. Clinical studies have found that the clinical pregnancy rate of endometrial thickness <7 mm is only 23.1%. In order to increase the thickness of the endometrium, in clinical practice, medical staff often use an intimal proliferation program, such as increasing the dose of estrogen, prolonging the estrogen use time, and combining low-dose aspirin.
However, there are always people who do not respond to the above treatment options and have difficulty reaching the thickness required for pregnancy. In order to squat this "hard bone", Liang Xiaoyan and her team developed an autologous stem cell transplant to help patients with intractable uterine endometrium to successfully conceive. In medical research, stem cells are immature primordial cells with self-renewal and multi-directional differentiation potential, and are pluripotent and can differentiate into cells of a particular lineage in a specific environment. Liang Xiaoyan said that autologous bone marrow mesenchymal stem cells are easy to obtain, have no ethical problems and have immunomodulatory functions, which contribute to the adjustment of endometrial receptivity.Liang Xiaoyan said that in previous animal experiments, they found that bone marrow mesenchymal stem cells can migrate to the uterus, increase endometrial thickness, and improve endometrial receptivity, and have the potential to treat thin endometrium, but due to technology Limitations have not been applied to the clinic. To date, 18 patients from all over the country have received intrauterine injections of autologous bone marrow stem cells, of which 6 patients have successfully gestated and 3 have had births.